Author Archives
Klaus D Linse , Ph.D
Director of Scientific Operations
klaus_linse@biosyn.com
www.biosyn.com
612 East Main Street, Lewisville, Texas 75057-4052
1-972-420-8505
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Q-FISHing to monitor molecular aging
By Klaus D. Linse Fluorescence In Situ Hybridization (FISH) for Telomere Length Quantification or Q-FISH evolves into High-Throughput Q-FISH Fluorescence in situ hybridization (FISH) is a powerful tool and probes that exhibit high DNA and RNA affinities promise to improve… Read More ›
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Synthetic peptides can be used to develop HIV tests
By Klaus D. Linse 01/04/12 Antigenic peptides from HIV-1/2 antigenic regions can be used to develop test for the detection of antibodies to HIV-1/2. Recently researchers located in India report that cocktails made from synthetic antigenic peptides from HIV1/2 antigens… Read More ›
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A brief history of Bridged Nucleic Acids (BNAs)
By Klaus D. Linse 01/03/2013 A quest for better oligonucleotide mimics. The quest for oligonucleotide mimics with improved characteristics and stabilities useful for molecular diagnostics and therapeutics that also show minimal side effects has led to the design and synthesis… Read More ›
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Peptide Based Vaccines For Immunotherapies
By Klaus D. Linse Can synthetic peptides be used for the development of vaccines against cancer cells? Many medical scientists think the answer is yes. In a study published by Schwartzentruber et al. in the “New England Journal of… Read More ›
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Can Leukemia be cured ?
T Cell Immunotherapy for Leukemia By Klaus D. Linse Scientists at Perelman School of medicine at the University of Pennsylvania have pioneered a new therapy for the cure of leukemia. The therapy is called the “T cell Immunotherapy for Leukemia.”… Read More ›
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Is protection against infection by HIV possible?
By Klaus D. Linse Wouldn’t it be cool to have a vaccine available to prevent infection by the HIV virus? Many research groups are feverishly working to devise a vaccine against the AIDS virus. But is this really achievable in… Read More ›
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Can Peptides Kill Cancer?
Australian researchers think so. By Klaus D Linse A research group in Melbourne Australia designed a peptide analogue derived from a Myxoma Virus protein that showed cytotoxicity towards mouse melanoma cells (Istivan et al., 2011; Almansour et al., 2012). Will… Read More ›
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Genes that define the shape of our face
Five gene loci appear to define the morphologic shape of a human face. According to Liu et al. in PLOS Genetics 2012|8|9|e1002932, they are located in and around the PRDM16 gene on chromosome 1, the chromosome 2 gene PAX3, TP63… Read More ›
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Artificial synthetic peptides as novel anti-HIV drugs?
Can synthetic peptides prevent HIV infections? Weiguo Shi’s group at the Department for Medicinal Chemistry at the Beijing Institute of Pharmacology & Toxicology thinks so. The group designed artificial peptides with the goal to prevent infection by the HIV virus… Read More ›
