Drosophila CRISPR Web Resources Name Link Description OxfCRISPR (Liu Lab) http://www.oxfcrispr.org Oxford Fly CRISPR Resources CRISPRflydesign (Bullock Lab) http://www.crisprflydesign.org/ Offers Cas9 transgenic stocks DRSC CRISPR finder (Perrimon Lab) http://www.flyrnai.org/crispr/ A web tool to identify CRISPRs for fly study FlyCas9 (Ueda… Read More ›
Cellular Reprogramming
Highlighted Reports on the CRISPR Cas System!
Selected papers for CRISPR Cas! Segal and Meckler in 2013 state in ‘Genome Engineering at the Dawn of the Golden Age,’ that, “In summary, compared with ZFNs, TALENs can be designed for more targets, are more likely to be active… Read More ›
Is Targeted Insertion of Short DNA Fragments into Mammalian Cells Possible?
Recently the Targeted Insertion of Short DNA Fragments into Mammalian Cells was Shown to be Possible with the help of CRISPR Cas! The direct injection of Cas9 mRNA, sgRNAs, and DNA oligos or vectors into mammalian cells was reported as… Read More ›
What is a CRISPR Cas system?
The CRISPR-Cas systems found in bacteria and archaea are versatile small RNAs for adaptive defense and regulation Bacteria and archaea have evolved various defense and regulatory mechanisms allowing them to react to various stressful situations caused by the environment, such… Read More ›
What are Nano-flares? What are the features of nano-flares?
Answer 1 . A “nano-flare” refers to a very small solar flare that happens in the corona, the external atmosphere of the Sun. . Answer 2 . Nano-flares are a new class of intracellular molecular probes. . This blog is… Read More ›
Piwi-RNAs, the Defenders of the Genome
What are Piwi- or piRNAs ? Here is the answer: P-element induced wimpy testis (Piwi)-RNAs, or Piwi-interacting RNA, or piRNAs are small RNAs typically 23 to 35 nucleotides long . . During the recent 16 years a group of small… Read More ›
What are Long or large non-coding RNAs (lncRNAs)?
Long or large non-coding RNAs (lncRNAs) are non-protein coding sequence transcripts ! . Long non-coding RNAs are non-protein coding sequence transcripts that contain more than 200 nucleotides. The size of these RNA molecules distinguishes them from small regulatory RNAs such… Read More ›
DNA Methylation
What is DNA Methylation? . DNA methylation is a biochemical reaction that adds a methyl group to DNA nucleotides. The methylation of DNA has been found to alter the expression of genes in cells during development. BSI can help you… Read More ›
What are MicroRNAs and what do they do?
MicroRNAs are small non-coding single-stranded RNA molecules MicroRNAs (miRNAs) are small non-coding single-stranded RNA molecules consisting of approximately 21 to 22 nucleotides that regulate posttranscriptional gene expression in metazoans and plants. miRNAs are usually generated from noncoding regions of gene… Read More ›
A New Approach to Cancer Therapy
Poster 5319 presented by Dr. Masamitsu Konno reports a new way for a cancer therapy to treat Gastrointestinal Cancer . The title of the poster presented in the AACR 2013 Meeting poster session on Wednesday morning in the section “Non-Coding… Read More ›
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