Shivarov et al. designed and validated a novel bead-based suspension assay using BNA[NC] probes for the Luminex Lab Scan 200 flow platform to detect and quantify somatic mutations in Leukemia! -.- Shivarov et al. recently develop and validated a novel bead-based… Read More ›
DNA Hybridization
What are Nano-flares? What are the features of nano-flares?
Answer 1 . A “nano-flare” refers to a very small solar flare that happens in the corona, the external atmosphere of the Sun. . Answer 2 . Nano-flares are a new class of intracellular molecular probes. . This blog is… Read More ›
Are viruses hiding within us?
Recent research results indicate that viral sequences are part of us. Endogenous viral elements (EVEs) or endogenous retroviral elements (ERVs) have been identified in eukaryotic genomes including the human genome. The findings revealed the enormous scale of the invasion of… Read More ›
RNA FISH can be used to visualize subcellular locations of RNA or RNA-RBP complexes including the location of noncoding RNAs !
RNA FISH allows the identification and localization of noncoding RNAs in cells ! Ribonucleic Acid Fluorescence In Situ Hybridization (RNA FISH) is a visualization technique that allows simultaneous detection, localization, and quantification of individual RNA molecules at the subcellular level…. Read More ›
Bridged Nucleic Acid based FISH
Bridged Nucleic Acid (BNA) based FISH probes are smart tools available from Biosynthesis Inc. Recent advancements in the design and development of molecular probes and image analysis has made fluorescence in situ hybridization (FISH) a powerful tool. Although being a… Read More ›
What are Long or large non-coding RNAs (lncRNAs)?
Long or large non-coding RNAs (lncRNAs) are non-protein coding sequence transcripts ! . Long non-coding RNAs are non-protein coding sequence transcripts that contain more than 200 nucleotides. The size of these RNA molecules distinguishes them from small regulatory RNAs such… Read More ›
DNA Methylation
What is DNA Methylation? . DNA methylation is a biochemical reaction that adds a methyl group to DNA nucleotides. The methylation of DNA has been found to alter the expression of genes in cells during development. BSI can help you… Read More ›