Teixobactin is a newly discovered natural occurring antibiotic peptide. Teixobactin is a newly discovered antibiotic peptide identified from soil samples using isolation chip (iChip, Ichip, or ichip) technology. In recent years, researchers developed the iChip technology to allow for the… Read More ›
Gene families
A novel BNA[NC] bead-based assay for somatic mutations in Leukemia
Shivarov et al. designed and validated a novel bead-based suspension assay using BNA[NC] probes for the Luminex Lab Scan 200 flow platform to detect and quantify somatic mutations in Leukemia! -.- Shivarov et al. recently develop and validated a novel bead-based… Read More ›
How can the CRISPR Cas System be used?
Potential Uses or Applications of the CRISPR Cas System ! -.- Several Uses of Cas9 Induced Double Strand Breaks for Genomic Engineering as Suggested by Basset and Li in 2014 are listed below. -.- Most applications of CRISPR Cas9 use… Read More ›
Structural Models of the CRISPR Cas System!
As of December 2013 90 solved structures were available in the PubMed structural database related to the CRISPR Cas System! -.- A few these models are shown below! A PubMed search for “CRISPR Cas” showed that close to 90 solved… Read More ›
Highlighted Reports on the CRISPR Cas System!
Selected papers for CRISPR Cas! Segal and Meckler in 2013 state in ‘Genome Engineering at the Dawn of the Golden Age,’ that, “In summary, compared with ZFNs, TALENs can be designed for more targets, are more likely to be active… Read More ›
What is a CRISPR Cas system?
The CRISPR-Cas systems found in bacteria and archaea are versatile small RNAs for adaptive defense and regulation Bacteria and archaea have evolved various defense and regulatory mechanisms allowing them to react to various stressful situations caused by the environment, such… Read More ›
How do we taste or smell odors?
The taste of sugars amino acids, peptides, nucleotides, and proteins “Analytical Services” Taste and smell are chemical senses that give us humans and many animals information about the chemical composition that surround us and are part of our nearest environment. … Read More ›
Are viruses hiding within us?
Recent research results indicate that viral sequences are part of us. Endogenous viral elements (EVEs) or endogenous retroviral elements (ERVs) have been identified in eukaryotic genomes including the human genome. The findings revealed the enormous scale of the invasion of… Read More ›
Piwi-RNAs, the Defenders of the Genome
What are Piwi- or piRNAs ? Here is the answer: P-element induced wimpy testis (Piwi)-RNAs, or Piwi-interacting RNA, or piRNAs are small RNAs typically 23 to 35 nucleotides long . . During the recent 16 years a group of small… Read More ›
Bridged Nucleic Acid based FISH
Bridged Nucleic Acid (BNA) based FISH probes are smart tools available from Biosynthesis Inc. Recent advancements in the design and development of molecular probes and image analysis has made fluorescence in situ hybridization (FISH) a powerful tool. Although being a… Read More ›