RNA FISH allows the identification and localization of noncoding RNAs in cells ! Ribonucleic Acid Fluorescence In Situ Hybridization (RNA FISH) is a visualization technique that allows simultaneous detection, localization, and quantification of individual RNA molecules at the subcellular level…. Read More ›
Genetics
What are Long or large non-coding RNAs (lncRNAs)?
Long or large non-coding RNAs (lncRNAs) are non-protein coding sequence transcripts ! . Long non-coding RNAs are non-protein coding sequence transcripts that contain more than 200 nucleotides. The size of these RNA molecules distinguishes them from small regulatory RNAs such… Read More ›
What is Aging? What are Aging Theories?
Have you ever asked yourself the following questions? . Why do we age? When do we start aging? Is there a biomarker for aging? Is there a limit to how old we can grow? . Many theories have been proposed… Read More ›
DNA Methylation
What is DNA Methylation? . DNA methylation is a biochemical reaction that adds a methyl group to DNA nucleotides. The methylation of DNA has been found to alter the expression of genes in cells during development. BSI can help you… Read More ›
Thermodynamics of DNA Hybridization
Knowledge of DNA thermodynamics is crucial for the design of PCR probes or any other oligonucleotide based hybridization probe! . Since DNA hybridization does not strictly follow the Watson-Crick pairing rules DNA hybridization experiments often require optimization. A DNA oligonucleotide… Read More ›
What are Micro peptides?
Micro peptides are short, unprocessed peptides with biological functions! . Do noncoding RNAs (ncRNAs) code for micro peptides? . Yes, apparently this appears to be the case! . In protein synthesis RNA acts as a template for cellular proteins and… Read More ›
What are MicroRNAs and what do they do?
MicroRNAs are small non-coding single-stranded RNA molecules MicroRNAs (miRNAs) are small non-coding single-stranded RNA molecules consisting of approximately 21 to 22 nucleotides that regulate posttranscriptional gene expression in metazoans and plants. miRNAs are usually generated from noncoding regions of gene… Read More ›
A New Approach to Cancer Therapy
Poster 5319 presented by Dr. Masamitsu Konno reports a new way for a cancer therapy to treat Gastrointestinal Cancer . The title of the poster presented in the AACR 2013 Meeting poster session on Wednesday morning in the section “Non-Coding… Read More ›
Peptides for Influenza Research
Synthetic peptides are versatile tools to help develop vaccines against new Influenza A viral strains Pools or libraries of synthetic peptides derived from Influenza A viral proteins can be used to screen for and identify human leukocyte class I (HLA-I)… Read More ›
Tales of Genes and Proteins
Implications of the Human Genome Project The human genome project revealed that the human genome contains approximately 26,000 to 38,000 genes that code for proteins. This is significantly fewer than had been previously anticipated. It was found that protein-coding sequences… Read More ›