Shivarov et al. designed and validated this BNA[NC] probe bead-based assay for the Luminex Lab Scan 200 flow platform to allow for the detection and quantification of somatic mutations in Leukemia! -.- How does the assay work? Primers are designed… Read More ›
Answer 1 . A “nano-flare” refers to a very small solar flare that happens in the corona, the external atmosphere of the Sun. . Answer 2 . Nano-flares are a new class of intracellular molecular probes. . This blog is… Read More ›
Recent research results indicate that viral sequences are part of us. Endogenous viral elements (EVEs) or endogenous retroviral elements (ERVs) have been identified in eukaryotic genomes including the human genome. The findings revealed the enormous scale of the invasion of… Read More ›
RNA FISH allows the identification and localization of noncoding RNAs in cells ! Ribonucleic Acid Fluorescence In Situ Hybridization (RNA FISH) is a visualization technique that allows simultaneous detection, localization, and quantification of individual RNA molecules at the subcellular level…. Read More ›
Bridged Nucleic Acid (BNA) based FISH probes are smart tools available from Biosynthesis Inc. Recent advancements in the design and development of molecular probes and image analysis has made fluorescence in situ hybridization (FISH) a powerful tool. Although being a… Read More ›
Long or large non-coding RNAs (lncRNAs) are non-protein coding sequence transcripts ! . Long non-coding RNAs are non-protein coding sequence transcripts that contain more than 200 nucleotides. The size of these RNA molecules distinguishes them from small regulatory RNAs such… Read More ›
What is DNA Methylation? . DNA methylation is a biochemical reaction that adds a methyl group to DNA nucleotides. The methylation of DNA has been found to alter the expression of genes in cells during development. BSI can help you… Read More ›
Knowledge of DNA thermodynamics is crucial for the design of PCR probes or any other oligonucleotide based hybridization probe! . Since DNA hybridization does not strictly follow the Watson-Crick pairing rules DNA hybridization experiments often require optimization. A DNA oligonucleotide… Read More ›
By Klaus D. Linse Fluorescence In Situ Hybridization (FISH) for Telomere Length Quantification or Q-FISH evolves into High-Throughput Q-FISH Fluorescence in situ hybridization (FISH) is a powerful tool and probes that exhibit high DNA and RNA affinities promise to improve… Read More ›
By Klaus D. Linse 01/04/12 Antigenic peptides from HIV-1/2 antigenic regions can be used to develop test for the detection of antibodies to HIV-1/2. Recently researchers located in India report that cocktails made from synthetic antigenic peptides from HIV1/2 antigens… Read More ›
