“3-phosphoglyceryl-lysine or pgK” is a newly discovered functional protein modification! The more scientists look the more they find ! . Can this new functional amino acid modification provide insights in the causes of diabetes, cancer, and other metabolic disorders in… Read More ›
Mass spectrometry
What is the “intelligent knife” also called “iKnife” or REIMS?
It is a new mass spectrometry based technique that could be used routinely for cancer diagnostics and surgery in the future! . It is a cancer knife that identifies tumor cells! . The news section of the Journal of Science… Read More ›
Which solid phase polypeptide synthesis do you like better? Fmoc- or tBoc-chemistry based?
It appears that Fmoc based solid phase polypeptide synthesis (SPPS) is the winner. … An evaluation of 53 different laboratories that synthesized polypeptides by members of the ‘ABRF Committee on Peptide Synthesis and Mass Spectrometry’ done in 1993 showed that… Read More ›
Why should I test my CHO cell culture for virus infections?
The answer is: … CHO cells can be infected in bioreactors with viruses such as Vesivirus 2117! … The presence of a virus in a bioreactor can inflict major losses for biotech and pharmaceutical companies involved in the manufacturing of… Read More ›
What are Long or large non-coding RNAs (lncRNAs)?
Long or large non-coding RNAs (lncRNAs) are non-protein coding sequence transcripts ! . Long non-coding RNAs are non-protein coding sequence transcripts that contain more than 200 nucleotides. The size of these RNA molecules distinguishes them from small regulatory RNAs such… Read More ›
DNA Methylation
What is DNA Methylation? . DNA methylation is a biochemical reaction that adds a methyl group to DNA nucleotides. The methylation of DNA has been found to alter the expression of genes in cells during development. BSI can help you… Read More ›
What are MicroRNAs and what do they do?
MicroRNAs are small non-coding single-stranded RNA molecules MicroRNAs (miRNAs) are small non-coding single-stranded RNA molecules consisting of approximately 21 to 22 nucleotides that regulate posttranscriptional gene expression in metazoans and plants. miRNAs are usually generated from noncoding regions of gene… Read More ›