non-coding RNAs

DNA Methylation


What is DNA Methylation? . DNA methylation is a biochemical reaction that adds a methyl group to DNA nucleotides. The methylation of DNA has been found to alter the expression of genes in cells during development. BSI can help you… Read More ›

What are Micro peptides?


Micro peptides are short, unprocessed peptides with biological functions! . Do noncoding RNAs (ncRNAs) code for micro peptides? . Yes, apparently this appears to be the case! . In protein synthesis RNA acts as a template for cellular proteins and… Read More ›

What are MicroRNAs and what do they do?


MicroRNAs are small non-coding single-stranded RNA molecules MicroRNAs (miRNAs) are small non-coding single-stranded RNA molecules consisting of approximately 21 to 22 nucleotides that regulate posttranscriptional gene expression in metazoans and plants. miRNAs are usually generated from noncoding regions of gene… Read More ›

What are MicroRNA sponges?


MicroRNA sponges are decoy targets for miRNA seed families ! Ebert, Neilson & Sharp in 2007 report how to make decoy targets for several microRNA seed families, and named them ‘microRNA sponges’. Furthermore the researchers tested their ability to derepress… Read More ›

What is a Gapmer?


A gapmer is a chimeric antisense oligonucleotide that contains a central block of deoxynucleotide monomers sufficiently long to induce RNase H cleavage. . Gapmers – Design and Use The central block of a gapmer is flanked by blocks of 2’-O… Read More ›