Gram-negative pathogens, such as Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii are now responsible for many infections, including infections occurring in hospitals. Because of their broad spectrum of antibiotic resistance many antibiotics may now longer work well. A few years after… Read More ›
peptides
Teixobactin, a new antibiotic peptide that has the potential to avoid the development of resistance
Teixobactin is a newly discovered natural occurring antibiotic peptide. Teixobactin is a newly discovered antibiotic peptide identified from soil samples using isolation chip (iChip, Ichip, or ichip) technology. In recent years, researchers developed the iChip technology to allow for the… Read More ›
Streptide, a newly discovered naturally occuring cyclic peptide
— … — Streptide is a newly discovered macrocyclic naturally occurring streptococcal peptide. Streptococcal bacteria are thought to use peptides as communication signals. Often these types of peptides contain unusual post-translational modifications. Many different biosynthetic strategies for the formation of… Read More ›
Peptides – a collection of words, nouns and terms to review – natural peptides, synthetic peptides, peptide mimics, artificial peptides, modified peptides and more.
WHAT ARE PEPTIDES? Peptides are macro molecules that contain amino acid monomers linked together by peptide (amide) bonds. The covalent bonds are formed when the carboxyl group of one amino acid reacts with the amino group of another. Peptides are… Read More ›
What is “3-phosphoglyceryl-lysine or pgK”?
“3-phosphoglyceryl-lysine or pgK” is a newly discovered functional protein modification! The more scientists look the more they find ! . Can this new functional amino acid modification provide insights in the causes of diabetes, cancer, and other metabolic disorders in… Read More ›
Which solid phase polypeptide synthesis do you like better? Fmoc- or tBoc-chemistry based?
It appears that Fmoc based solid phase polypeptide synthesis (SPPS) is the winner. … An evaluation of 53 different laboratories that synthesized polypeptides by members of the ‘ABRF Committee on Peptide Synthesis and Mass Spectrometry’ done in 1993 showed that… Read More ›
Why should I test my CHO cell culture for virus infections?
The answer is: … CHO cells can be infected in bioreactors with viruses such as Vesivirus 2117! … The presence of a virus in a bioreactor can inflict major losses for biotech and pharmaceutical companies involved in the manufacturing of… Read More ›
What are Micro peptides?
Micro peptides are short, unprocessed peptides with biological functions! . Do noncoding RNAs (ncRNAs) code for micro peptides? . Yes, apparently this appears to be the case! . In protein synthesis RNA acts as a template for cellular proteins and… Read More ›
Why are some infections with certain flu virus strains fatal and others are not?
The answer may be found in human CD4+ T cells Virus specific memory CD4+ T cells numbers predict the outcome of human influenza infections Wilkinson et al. in 2012 showed that CD4+ T cells that are activated by earlier influenza virus… Read More ›
Peptide Property Calculator
Peptide Property Calculator Peptide property calculator is a comprehensive web-based tool available at Biosynthesis which calculates the various physiochemical property of the protein sequence. Listed below are the application user can access from the tool: Calculates the physiochemical properties like… Read More ›