WHAT ARE PEPTIDES? Peptides are macro molecules that contain amino acid monomers linked together by peptide (amide) bonds. The covalent bonds are formed when the carboxyl group of one amino acid reacts with the amino group of another. Peptides are… Read More ›
Stapled Peptides
What is “3-phosphoglyceryl-lysine or pgK”?
“3-phosphoglyceryl-lysine or pgK” is a newly discovered functional protein modification! The more scientists look the more they find ! . Can this new functional amino acid modification provide insights in the causes of diabetes, cancer, and other metabolic disorders in… Read More ›
Which solid phase polypeptide synthesis do you like better? Fmoc- or tBoc-chemistry based?
It appears that Fmoc based solid phase polypeptide synthesis (SPPS) is the winner. … An evaluation of 53 different laboratories that synthesized polypeptides by members of the ‘ABRF Committee on Peptide Synthesis and Mass Spectrometry’ done in 1993 showed that… Read More ›
News from the AACR meeting 2013 in Washington, DC
The AACR 2013 Meeting in Washington DC To find out about AACR you can click on this link: http://www.aacr.org/home/about-us.aspx News from the AACR 2013 Meeting The AACR publishes progress reports on the development of cancer occurrences and advancements made in… Read More ›
Stapled Peptides
Peptide mimics useful for the modulation of protein and receptor signaling and subsequent gene expression By Klaus D. Linse Synthetic peptides that specifically bind to proteins such as cytokines, protein hormones, and nuclear hormone receptors offer an alternative approach to… Read More ›