WHAT ARE PEPTIDES? Peptides are macro molecules that contain amino acid monomers linked together by peptide (amide) bonds. The covalent bonds are formed when the carboxyl group of one amino acid reacts with the amino group of another. Peptides are… Read More ›
custom peptide
What is “3-phosphoglyceryl-lysine or pgK”?
“3-phosphoglyceryl-lysine or pgK” is a newly discovered functional protein modification! The more scientists look the more they find ! . Can this new functional amino acid modification provide insights in the causes of diabetes, cancer, and other metabolic disorders in… Read More ›
Which solid phase polypeptide synthesis do you like better? Fmoc- or tBoc-chemistry based?
It appears that Fmoc based solid phase polypeptide synthesis (SPPS) is the winner. … An evaluation of 53 different laboratories that synthesized polypeptides by members of the ‘ABRF Committee on Peptide Synthesis and Mass Spectrometry’ done in 1993 showed that… Read More ›
What are Micro peptides?
Micro peptides are short, unprocessed peptides with biological functions! . Do noncoding RNAs (ncRNAs) code for micro peptides? . Yes, apparently this appears to be the case! . In protein synthesis RNA acts as a template for cellular proteins and… Read More ›
Peptides for Influenza Research
Synthetic peptides are versatile tools to help develop vaccines against new Influenza A viral strains Pools or libraries of synthetic peptides derived from Influenza A viral proteins can be used to screen for and identify human leukocyte class I (HLA-I)… Read More ›
Stapled Peptides
Peptide mimics useful for the modulation of protein and receptor signaling and subsequent gene expression By Klaus D. Linse Synthetic peptides that specifically bind to proteins such as cytokines, protein hormones, and nuclear hormone receptors offer an alternative approach to… Read More ›
Synthetic peptides can be used to develop HIV tests
By Klaus D. Linse 01/04/12 Antigenic peptides from HIV-1/2 antigenic regions can be used to develop test for the detection of antibodies to HIV-1/2. Recently researchers located in India report that cocktails made from synthetic antigenic peptides from HIV1/2 antigens… Read More ›
Peptide Based Vaccines For Immunotherapies
By Klaus D. Linse Can synthetic peptides be used for the development of vaccines against cancer cells? Many medical scientists think the answer is yes. In a study published by Schwartzentruber et al. in the “New England Journal of… Read More ›
Artificial synthetic peptides as novel anti-HIV drugs?
Can synthetic peptides prevent HIV infections? Weiguo Shi’s group at the Department for Medicinal Chemistry at the Beijing Institute of Pharmacology & Toxicology thinks so. The group designed artificial peptides with the goal to prevent infection by the HIV virus… Read More ›