The taste of sugars amino acids, peptides, nucleotides, and proteins “Analytical Services” Taste and smell are chemical senses that give us humans and many animals information about the chemical composition that surround us and are part of our nearest environment. … Read More ›
Circular oligonucleotides are covalently closed singular DNA or RNA strands that are resistant to degradation by many cellular DNA and RNA decay machineries. [Source: (left) Modelling DNA; Phil. Trans. R. Soc. A-2006-Harris-3319-34; (right) David Goodsell: The self-splicing RNA in PDB… Read More ›
The answer is: … CHO cells can be infected in bioreactors with viruses such as Vesivirus 2117! … The presence of a virus in a bioreactor can inflict major losses for biotech and pharmaceutical companies involved in the manufacturing of… Read More ›
RNA FISH can be used to visualize subcellular locations of RNA or RNA-RBP complexes including the location of noncoding RNAs !
RNA FISH allows the identification and localization of noncoding RNAs in cells ! Ribonucleic Acid Fluorescence In Situ Hybridization (RNA FISH) is a visualization technique that allows simultaneous detection, localization, and quantification of individual RNA molecules at the subcellular level…. Read More ›
Oligo Designer Oligo Desinger is a comprehensive web-based tool available at Biosynthesis which calculates the various physiochemical properties of oligonucleotides based on their sequence. Listed below are the application user can access from the tool: Calculates the chemical formula Calculates… Read More ›
Knowledge of DNA thermodynamics is crucial for the design of PCR probes or any other oligonucleotide based hybridization probe! . Since DNA hybridization does not strictly follow the Watson-Crick pairing rules DNA hybridization experiments often require optimization. A DNA oligonucleotide… Read More ›