Oligo Synthesis

Happy DNA Week!


This week is the international DNA week! . This year we celebrate the 60th anniversary of the discovery of the DNA double helix by Watson and Crick which was achieved with the help of X-ray diffraction data produced by Rosalind… Read More ›

What is a Gapmer?


A gapmer is a chimeric antisense oligonucleotide that contains a central block of deoxynucleotide monomers sufficiently long to induce RNase H cleavage. . Gapmers – Design and Use The central block of a gapmer is flanked by blocks of 2’-O… Read More ›

What are microRNA (miRNA) mimics?


MicroRNA (miRNA) mimics are innovative biomolecules useful for research in gene targeting, antisense and cell reprogramming approches miRNA mimics are innovative molecules designed for gene silencing approaches. miRNA mimics contain nonnatural or  artificial double stranded miRNA-like RNA fragments. These RNA… Read More ›