Happy DNA Week!

This week is the international DNA week! . This year we celebrate the 60th anniversary of the discovery of the DNA double helix by Watson and Crick which was achieved with the help of X-ray diffraction data produced by Rosalind… Read More ›

What is a Gapmer?

A gapmer is a chimeric antisense oligonucleotide that contains a central block of deoxynucleotide monomers sufficiently long to induce RNase H cleavage. . Gapmers – Design and Use The central block of a gapmer is flanked by blocks of 2’-O… Read More ›

How can MicroRNAs be descriped?

Nomenclature of MicroRNAs Since hundreds of human miRNAs and thousands across other species have been identified, a system of nomenclature has been adopted and names are designated to specific miRNAs before publication of their discovery. Foe annotation experimentally confirmed microRNAs… Read More ›